HYDROXYLAMINE HYDROCHLORIDE
MSDS Number: H5960 --- Effective Date: 03/26/99
1. Product Identification
Synonyms: Oxammonium hydrochloride; hydroxylammonium chloride
CAS No.: 5470-11-1
Molecular Weight: 69.5
Chemical Formula: NH2OH HCl
Product Codes:
J.T. Baker:
2195, 2196
Mallinckrodt:
5258
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Hydroxylamine, Hydrochloride 5470-11-1 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
DANGER! CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. HARMFUL IF
SWALLOWED OR INHALED. AFFECTS THE BLOOD. MAY CAUSE METHEMOGLOBINEMIA.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Poison)
Flammability Rating: 2 - Moderate
Reactivity Rating: 2 - Moderate
Contact Rating: 3 - Severe (Corrosive)
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: White (Corrosive)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Inhalation:
Corrosive. Extremely destructive to tissues of the mucous membranes and
upper respiratory tract. Symptoms may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea and vomiting.
Inhalation may be fatal as a result of spasm inflammation and edema of the
larynx and bronchi, chemical pneumonitis and pulmonary edema.
Ingestion:
May convert hemoglobin to methemoglobin, producing cyanosis. May also cause
nausea, vomiting, fall in blood pressure, headache, vertigo, ringing in the
ears, shortness of breath, severe blood oxygen deficiency and convulsions.
High concentrations cause coma and death from circulatory collapse.
Skin Contact:
Irritant and possible sensitizer. May cause burns.
Eye Contact:
Corrosive to the eyes. May cause severe irritation and corneal damage.
Chronic Exposure:
This substance is a blood toxin, causing hemoglobin to convert to
methemoglobin, resulting in cyanosis. Lengthy or repeated exposures may
result in decreased appetite, anemia, weight loss, nervous system affects,
and kidney, liver and bone marrow damage.
Aggravation of Pre-existing Conditions:
Persons with pre-existing disorders of the blood, skin, liver, kidneys or
lungs may be at an increased risk from exposure.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical attention immediately.
Ingestion:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never
give anything by mouth to an unconscious person. Get medical attention
immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Get medical attention
immediately. Wash clothing before reuse. Thoroughly clean shoes before
reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.
Note to Physician:
Provide general supportive measures and treat symptomatically. In cases of
ingestion, the decision of whether or not to induce vomiting should be made
by the attending physician. If burn is present, treat as a thermal burn.
Removing adhered product from burned skin may compromise the skin integrity
and result in infection and/or more severe scarring.
5. Fire Fighting Measures
Fire:
Not considered to be a fire hazard. As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion:
Contact with strong oxidizing materials may cause extremely violent
combustion. May explode when heated to 140C (284F). Fine dust dispersed in
air in sufficient concentrations, and in the presence of an ignition source
is a potential dust explosion hazard.
Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire. Water spray may
be used to extinguish surrounding fire and cool exposed containers. Water
spray will also reduce fume and irritant gases.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.
6. Accidental Release Measures
Remove all sources of ignition. Ventilate area of leak or spill. Wear
appropriate personal protective equipment as specified in Section 8.
Spills: Clean up spills in a manner that does not disperse dust into the
air. Use non-sparking tools and equipment. Reduce airborne dust and prevent
scattering by moistening with water. Pick up spill for recovery or disposal
and place in a closed container.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area.
Protect against physical damage. Isolate from any source of heat or
ignition. Isolate from oxidizing materials. Avoid dust formation and
control ignition sources. Employ grounding, venting and explosion relief
provisions in accord with accepted engineering practices in any process
capable of generating dust and/or static electricity. Empty only into inert
or non-flammable atmosphere. Emptying contents into a non-inert atmosphere
where flammable vapors may be present could cause a flash fire or explosion
due to electrostatic discharge.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures as low as possible. Local exhaust ventilation is generally
preferred because it can control the emissions of the contaminant at its
source, preventing dispersion of it into the general work area. Please
refer to the ACGIH document, Industrial Ventilation, A Manual of
Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent, a
half-face dust/mist respirator may be worn. For emergencies or instances
where the exposure levels are not known, use a full-face positive-pressure,
air-supplied respirator. WARNING: Air-purifying respirators do not
protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or
splashing of solutions is possible. Maintain eye wash fountain and
quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Hygroscopic, colorless to slightly yellow crystals.
Odor:
Odorless.
Solubility:
83 g/100 mg water @ 17C (63F); slowly decomposes.
Density:
1.67
pH:
3.2 (0.2 M solution)
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
305.6C (583F)
Melting Point:
155 - 157C (311 - 315F) Decomposes.
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage. Slowly decomposes when
moist.
Hazardous Decomposition Products:
Emits toxic fumes of nitrogen oxides and hydrogen chloride when heated to
decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizing agents, heat plus sodium acetate or ether, carbonyl
compounds, copper sulfate, zinc and phosphorus chlorides.
Conditions to Avoid:
Heat, flame, moisture, dusting, sources of ignition and shock, and
incompatibles.
11. Toxicological Information
Hydroxylamine hydrochloride: oral mouse LD50: 408 mg/kg; Oral rat LD50:
141 mg/kg; Investigated as a mutagen.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Hydroxylamine, Hydrochloride No No None
(5470-11-1)
12. Ecological Information
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an
appropriate and approved waste disposal facility. Processing, use or
contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: CORROSIVE SOLID,TOXIC, N.O.S. (HYDROXYLAMINE
HYDROCHLORIDE)
Hazard Class: 8, 6.1
UN/NA: UN2923
Packing Group: III
Information reported for product/size: 2.5KG
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: CORROSIVE SOLID,TOXIC, N.O.S. (HYDROXYLAMINE
HYDROCHLORIDE)
Hazard Class: 8, 6.1
UN/NA: UN2923
Packing Group: III
Information reported for product/size: 2.5KG
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Hydroxylamine, Hydrochloride (5470-11-1) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Hydroxylamine, Hydrochloride (5470-11-1) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Hydroxylamine, Hydrochloride (5470-11-1) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Hydroxylamine, Hydrochloride No No No
(5470-11-1)
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: Yes (Pure / Solid)
Australian Hazchem Code: 2X
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 3 Flammability: 1 Reactivity: 1
Label Hazard Warning:
DANGER! CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. HARMFUL IF SWALLOWED
OR INHALED. AFFECTS THE BLOOD. MAY CAUSE METHEMOGLOBINEMIA.
Label Precautions:
Do not breathe dust.
Wash thoroughly after handling.
Do not get in eyes, on skin, or on clothing.
Keep container closed.
Use only with adequate ventilation.
Label First Aid:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never
give anything by mouth to an unconscious person. In case of contact,
immediately flush eyes or skin with plenty of water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before reuse.
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In all cases get medical
attention immediately.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 3, 4, 5,
8, 9, 14, 16.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or accuracy.
This document is intended only as a guide to the appropriate precautionary
handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment
in determining its appropriateness for a particular purpose. MALLINCKRODT
BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
************************************************************************************************
Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)