Fisher Scientific Back to 1,2,4-Trichlorobenzene, 99% 
Material Safety Data Sheet
1,2,4-Trichlorobenzene, 99%

ACC# 95590
Section 1 - Chemical Product and Company Identification
MSDS Name: 1,2,4-Trichlorobenzene, 99%
Catalog Numbers: AC157900000, AC157900010, AC157900025
Synonyms:
unsym-Trichlorobenzene
Company Identification:

       Acros Organics N.V.
       One Reagent Lane
       Fairlawn, NJ 07410
For information in North America, call: 800-ACROS-01
For information in Europe, call: 0032(0) 14575211
For emergencies in the US, call CHEMTREC: 800-424-9300
For emergencies outside the US, call: 0032(0) 14575299

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
120-82-11,2,4-TRICHLOROBENZENE 99% 204-428-0
Hazard Symbols: XN
Risk Phrases:
22 38 51/53

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear, colorless. Caution! May be harmful if swallowed. May causecentral nervous system depression. Causes severe eye irritation.Causes digestive and respiratory tract irritation. May cause blurredvision. May cause severe skin irritation.
Target Organs: Kidneys, central nervous system,liver.

Potential Health Effects

Eye: May cause severe eye irritation.
Skin: Causes skin irritation. May cause dermatitis.
Ingestion: Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause a narcotic effect with possible coma. May cause central nervous system depression.
Inhalation: May cause respiratory tract irritation.
Chronic: Prolonged or repeated skin contact may cause dermatitis. May cause liver and kidney damage.

Section 4 - First Aid Measures


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower lids. Get medical aid immediately.
Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Do NOT adminster adrenaline after exposure via inhalation or ingestion.

Section 5 - Firefighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Combustible material; may burn but does not ignite readily.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, halon, or water spray. Do NOT get water inside containers. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Autoignition Temperature: 571 deg C (1,059.80 deg F)
Flash Point: 110 deg C (230.00 deg F)(estimated) Health: 2; Flammability: 1; Reactivity: 0 Explosion Limits, Lower: 2.50 vol % Upper: 6.60 vol %

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation. Do not get water inside containers.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
1,2,4-TRICHLOROBENZENEC 5 ppm; C 37 mg/m3none listednone listed

OSHA Vacated PELs: 1,2,4-TRICHLOROBENZENE: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear, colorless
Odor: Characteristic aromatic odor
pH: Not available.
Vapor Pressure: 2 hPa @ 50 deg C
Vapor Density: 6.26
Evaporation Rate:
Viscosity: Not available.
Boiling Point: 214760.00 deg C
Freezing/Melting Point:16 deg C
Decomposition Temperature:Not available.
Solubility: insoluble
Specific Gravity/Density:1.4540g/cm3
Molecular Formula:C6H3Cl3
Molecular Weight:

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: High temperatures, incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:
CAS# 120-82-1: DC2100000
LD50/LC50:
CAS# 120-82-1:
Oral, mouse: LD50 = 300 mg/kg;
Oral, rat: LD50 = 756 mg/kg;
Skin, rat: LD50 = 6139 mg/kg;
Carcinogenicity:
CAS# 120-82-1: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: orl-rat TDL0: 1800 mg/kg (9-13D preg) ipr-rat TDL0: 750 mg/kg (3D pre)
Neurotoxicity: No information available.
Mutagenicity: mnt-mus-ipr: 210 mg/kg/24H
Other Studies: No data available.

Section 12 - Ecological Information


Ecotoxicity: Acute fish toxicity: LC50 on Poecilia reticula: approx. 2,4 mg/l. Duration of test: 14 d (Verschueren,K. Handb.of Environm. Data on Org.Chem., 2 ed., 1983); LC50 on Lepomis macrochirus: approx. 3,4 mg/l (Buccafusco,R.J. et al. Bull.Environm.Toxicol.26,446-452,1981).
Environmental Fate: According to WORNE biological degradation with complete ring cleavage occurs within 46 hours at 30xC in the presence of Pseudomonas sp. The test was conducted with adapted bacteria (Worne,H.E. Magazine from BECEWA, Liege, Belgium 22, 1972, 61-71).
Physical/Chemical: Not available.
Other: Not available.

Section 13 - Disposal Considerations

Dispose of in a manner consistent with federal, state, and local regulations.
RCRA D-Series Maximum Concentration ofContaminants: None listed.
RCRA D-Series Chronic Toxicity ReferenceLevels: None listed.
RCRA F-Series: None listed.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT IATA RID/ADR IMO Canada TDG
Shipping Name:TRICHLOROBENZENES, LIQUIDTRICHLOROBENZENES, LIQUIDTRICHLOROBENZENES, LIQUIDTRICHLOROBENZENES, LIQUIDTRICHLOROBENZENES, LIQUID
Hazard Class:6.16.16.1(15C)6.16.1
UN Number:UN2321UN2321UN2321UN2321UN2321
Packing Group:IIIIIIIIIIII

Section 15 - Regulatory Information

US FEDERAL

TSCA
CAS# 120-82-1 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
CAS# 120-82-1: Testing required by: manufacturers; processors (40 CFR 799.1
Section 12b
CAS# 120-82-1: export notification required - Section 4
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA

Section 302 (RQ)
CAS# 120-82-1: final RQ = 100 pounds (45.4 kg)
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 120-82-1: acute, chronic.
Section 313
This material contains 1,2,4-TRICHLOROBENZENE (CAS# 120-82-1, 99%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 120-82-1 is listed as a hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA. CAS# 120-82-1 is listed as a Priority Pollutant under the Clean Water Act. None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 120-82-1 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:

R 22 Harmful if swallowed. R 38 Irritating to skin. R 51/53 Toxic to aquatic organisms; may cause long-term adverse effects in the aquatic environment.
Safety Phrases:

S 36/37 Wear suitable protective clothing and gloves. S 61 Avoid release to the environment. Refer to special instructions/Safety data sheets.
WGK (Water Danger/Protection)

CAS# 120-82-1: 3
Canada
CAS# 120-82-1 is listed on Canada's DSL/NDSL List.
This product does not have a WHMIS classification.
CAS# 120-82-1 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 120-82-1: OEL-AUSTRALIA:TWA 5 ppm (40 mg/m3) OEL-BELGIUM:STEL
5 ppm (37 mg/m3) OEL-DENMARK:TWA 5 ppm (40 mg/m3) OEL-FINLAND:TWA 5
ppm (40 mg/m3);STEL 10 ppm (74 mg/m3);Skin OEL-FRANCE:TWA 5 ppm (40 m
g/m3) OEL-GERMANY:TWA 5 ppm (40 mg/m3) OEL-THE NETHERLANDS:TWA 5 ppm
(40 mg/m3) OEL-SWITZERLAND:TWA 5 ppm (40 mg/m3) OEL-UNITED KINGDOM:
TWA 5 ppm (40 mg/m3);STEL 5 pp (40 mg/m3) OEL IN BULGARIA, COLOMBIA,
JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM
check ACGI TLV

Section 16 - Additional Information

MSDS Creation Date: 11/24/1995
Revision #3 Date: 9/08/1998
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.